Yep, I got that same exact bug just now, it happened to me when I saved outside of that one mansion with that little blonde girl. It seems that talking to her while outside of the mansion causes some kind of bug that just causes the game to shut down. Well, whenever you save your game, you automatically speak to whatever person is accompanying you. So, since I saved my game outside of the mansion, now whenever I try to reload, the game immediately makes me talk to this girl, causing my game to immediately shut down.
EDIT: Thankfully, I had that backup thing going, and thank you to BRS for letting me know how the backups worked, so everything's working now.
Game.rxdata